abstract：:A case of life-threatening lower gastrointestinal hemorrhage from Crohn's disease is reported. Several promising studies have recently been published that describe superselective embolization for the treatment of massive lower gastrointestinal hemorrhage in patients with bleeding colonic diverticular disease and angio...

journal_title：Journal of gastroenterology

authors： Kazama Y,Watanabe T,Akahane M,Yoshioka N,Ohtomo K,Nagawa H

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Percutaneous microwave ablation and radiofrequency ablation are two commonly used modalities for the treatment of hepatocellular carcinoma; however, comparisons of them have not been documented adequately. METHODS:Of 102 patients with biopsy-proved hepatocellular carcinoma, 49 (98 nodules) were treated perc...

journal_title：Journal of gastroenterology

authors： Lu MD,Xu HX,Xie XY,Yin XY,Chen JW,Kuang M,Xu ZF,Liu GJ,Zheng YL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Although previous studies have indicated that serum pepsinogen I levels, as well as the pepsinogen I/II ratio, were positively correlated with maximal gastric output, the relationship may be different between Helicobacter pylori-negative and -positive subjects. The aim of this study was to investigate the re...

journal_title：Journal of gastroenterology

authors： Iijima K,Sekine H,Koike T,Imatani A,Ohara S,Shimosegawa T

更新日期：2005-10-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pelvic coil and an endorectal coil were consistent with pathologic findings. MRI with a pelvic coil demon...

journal_title：Journal of gastroenterology

authors： Matsuoka H,Nakamura A,Iwamoto K,Sugiyama M,Hachiya J,Atomi Y,Masaki T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:At clinical scintigraphic examinations of the abdomen using single photon emission computed tomography (SPECT), we have observed a different distribution between the left and right main liver lobes of various radiopharmaceuticals. This was studied retrospectively in clinical patients. METHODS:Examinations w...

journal_title：Journal of gastroenterology

authors： Jacobsson H,Jonas E,Hellström PM,Larsson SA

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The remnant stomach corresponds to the gastric cardia, but is exposed to a completely different environment. The present study was performed to investigate the role of Epstein-Barr virus (EBV) infection in patients with gastric remnant carcinoma (GRC). METHODS:Clinicopathological features, gastritis, and in...

journal_title：Journal of gastroenterology

authors： Kaizaki Y,Hosokawa O,Sakurai S,Fukayama M

更新日期：2005-06-01 00:00:00

abstract：:We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

journal_title：Journal of gastroenterology

authors： Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Rice extract has been shown to protect gastric mucosa from stress-induced damage. In this study, the antibiotic effect and the anti-inflammatory effect of orally administered aqueous rice extract on Helicobacter pylori infection and H. pylori-induced gastritis, respectively, in Mongolian gerbils were investi...

journal_title：Journal of gastroenterology

authors： Murakami M,Ota H,Sugiyama A,Ishizone S,Maruta F,Akita N,Okimura Y,Kumagai T,Jo M,Tokuyama T

更新日期：2005-05-01 00:00:00

abstract：:Pyogenic granulomas represent the aquisition of vasodilative granulation tissue in the skin or mucosa. They are extremely rare in the alimentary tract, other than in the oral cavity. Here, we report a case of pyogenic granuloma arising from the gastric mucosa. An 82-year-old man was admitted to our hospital because of...

journal_title：Journal of gastroenterology

authors： Kusakabe A,Kato H,Hayashi K,Igami T,Hasegawa H,Tsuzuki T,Ueda R,Mizokami M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The T-helper (Th)1 immune reaction is essential for the eradication of hepatitis C virus (HCV) during interferon (IFN) therapy in patients with chronic hepatitis C. Osteopontin is a cytokine crucial for the initiation of the Th1 response. Recently, we identified four single-nucleotide polymorphisms (SNPs) in...

journal_title：Journal of gastroenterology

authors： Naito M,Matsui A,Inao M,Nagoshi S,Nagano M,Ito N,Egashira T,Hashimoto M,Mishiro S,Mochida S,Fujiwara K

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Ghrelin is a novel 28-amino-acid peptide isolated from rat and human stomach. This peptide is an endogenous ligand for the growth hormone secretagogue receptor and stimulates the release of growth hormones. Although the principal site of ghrelin synthesis has been reported to be in the stomach, there have be...

journal_title：Journal of gastroenterology

authors： Tanaka-Shintani M,Watanabe M

更新日期：2005-04-01 00:00:00

abstract：:In Japan, nutritional therapy as both a primary and as a secondary treatment is widely used for Crohn's disease (CD). The rationale for its use is based on a variety of reasons. The first is its ability to induce remission and to ameliorate the activity of intestinal lesions in the short term by enteral (EN) or by par...

journal_title：Journal of gastroenterology

authors： Matsui T,Sakurai T,Yao T

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Few epidemiologic studies have examined the role of nutrient intake in the development of pancreatic cancer in Japan. We addressed this association in a population-based case-control study. METHODS:The cases were 109 patients who were newly diagnosed with pancreatic cancer between January 2000 and March 200...

journal_title：Journal of gastroenterology

authors： Lin Y,Tamakoshi A,Hayakawa T,Naruse S,Kitagawa M,Ohno Y

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is histopathologically characterized by chronic nonsuppurative destructive cholangitis and ductopenia of interlobular bile ducts. Bile duct injury is also often encountered in chronic viral hepatitis (CVH) and in autoimmune hepatitis (AIH). METHODS:In this study, we performed...

journal_title：Journal of gastroenterology

authors： Zen Y,Harada K,Sasaki M,Tsuneyama K,Matsui K,Haratake J,Sakisaka S,Maeyama S,Yamamoto K,Nakano M,Shimamatsu K,Kage M,Kurose N,Uchiyama A,Kaizaki Y,Toda G,Nakanuma Y

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Contrast-enhanced echocardiography (CEE) using agitated saline can detect intrapulmonary vasodilatation (IPVD) in patients with hepatopulmonary syndrome (HPS). We estimated the pulmonary transit time of erythrocytes (PTT) by CEE, using microbubbles, and studied its relationship to arterial oxygenation in chr...

journal_title：Journal of gastroenterology

authors： Katsuta Y,Honma H,Zhang XJ,Ohsuga M,Komeichi H,Shimizu S,Katoh Y,Miura H,Satomura K,Aramaki T,Takano T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:We carried out this study to evaluate recent clinical features of Wilson's disease (WD) with hepatic presentation, especially in terms of age, degree of liver injury, and association with hepatocellular carcinoma (HCC). METHODS:Sixteen patients with hepatic manifestations were diagnosed with WD in the perio...

journal_title：Journal of gastroenterology

authors： Kumagi T,Horiike N,Michitaka K,Hasebe A,Kawai K,Tokumoto Y,Nakanishi S,Furukawa S,Hiasa Y,Matsui H,Kurose K,Matsuura B,Onji M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:In Japan, generally, patients with chronic hepatitis C are aged. The aim of this study was to investigate the effect of interferon (IFN) therapy on the mortality of chronic hepatitis C patients over age 60. METHODS:Seven-hundred and seven patients with histologically proven chronic hepatitis C were enrolled...

journal_title：Journal of gastroenterology

authors： Imai Y,Kasahara A,Tanaka H,Okanoue T,Hiramatsu N,Tsubouchi H,Yoshioka K,Kawata S,Tanaka E,Hino K,Hayashi K,Tamura S,Itoh Y,Sasaki Y,Kiyosawa K,Kakumu S,Okita K,Hayashi N

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:In Japan, there are few studies of long-term (more than 1 month) interferon (IFN) therapy for chronic hepatitis B (CHB). In this retrospective study, we investigated the efficacy and predictors of response to 6-month IFN therapy. METHODS:We analyzed 66 Japanese patients with CHB who were treated with IFN fo...

journal_title：Journal of gastroenterology

authors： Suzuki F,Arase Y,Akuta N,Tsubota A,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Ikeda K,Kobayashi M,Matsuda M,Satoh J,Kumada H

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Infection with Helicobacter pylori has been associated with chronic idiopathic urticaria (CIU). The aim of this study was to investigate the efficacy of H. pylori eradication in the treatment of patients with CIU. METHODS:Fifty patients with CIU (16 men and 34 women; age 25-75 years) and 100 sex- and age-ma...

journal_title：Journal of gastroenterology

authors： Fukuda S,Shimoyama T,Umegaki N,Mikami T,Nakano H,Munakata A

更新日期：2004-09-01 00:00:00

abstract：:Black liver is a common finding in Dubin-Johnson syndrome (DJS), which is caused by the lack of multidrug resistance-associated protein 2 (MRP2). Impaired excretion of epinephrine metabolites is believed to be a cause of black liver in DJS. Recently, we experienced a patient with black liver whose serum bilirubin leve...

journal_title：Journal of gastroenterology

authors： Kobayashi Y,Ishihara T,Wada M,Kajihara S,Araki J,Mifuji R,Itani T,Kuroda M,Urawa F,Kaito M,Adachi Y

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The gap junction (GJ) plays important roles in the maintenance of tissue homeostasis, the control of cell growth and differentiation, and the prevention of experimental hepatocarcinogenesis. In this study, we examined the relationship between the expression of the GJ protein connexin (Cx) 32 in 24 human hepa...

journal_title：Journal of gastroenterology

authors： Nakashima Y,Ono T,Yamanoi A,El-Assal ON,Kohno H,Nagasue N

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Because of the wide overlap between the groups, patients with reflux esophagitis (RE) cannot be distinguished from healthy subjects by basal lower esophageal sphincter (LES) pressure. The LES has radial asymmetry, with maximum pressure on the left side. It has been noted that one directional LES pressure, de...

journal_title：Journal of gastroenterology

authors： Iwakiri K,Hayashi Y,Kotoyori M,Sugiura T,Kawakami A,Sakamoto C

更新日期：2004-07-01 00:00:00

abstract：:We report a 54-year-old Japanese woman who developed liver tumors 102 months after hepatic resection for hepatocellular carcinoma (HCC) and percutaneous transluminal angioplasty (PTA) for membranous obstruction of the inferior vena cava (MOVC), which is one form of Budd-Chiari syndrome. In the present admission workup...

journal_title：Journal of gastroenterology

authors： Takamura M,Ichida T,Yokoyama J,Matsuda Y,Nomoto M,Aoyagi Y

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Depth of submucosal invasion (SM depth) in submucosal invasive colorectal carcinoma (SICC) is considered an important predictive factor for lymph node metastasis. However, no nationwide reports have clarified the relationship between SM depth and rate of lymph node metastasis. Our aim was to investigate the ...

journal_title：Journal of gastroenterology

authors： Kitajima K,Fujimori T,Fujii S,Takeda J,Ohkura Y,Kawamata H,Kumamoto T,Ishiguro S,Kato Y,Shimoda T,Iwashita A,Ajioka Y,Watanabe H,Watanabe T,Muto T,Nagasako K

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Polymorphisms in the gene for interleukin 1beta (IL-1B) have been found to increase the risks of gastric cancer and its precursors in response to Helicobacter pylori infection in white populations. however, there has been no independent confirmation of the role of IL-1B markers in gastric cancer patients fro...

journal_title：Journal of gastroenterology

authors： Lee KA,Ki CS,Kim HJ,Sohn KM,Kim JW,Kang WK,Rhee JC,Song SY,Sohn TS

更新日期：2004-01-01 00:00:00

abstract：:We report a case of primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome with concurrent idiopathic thrombocytopenic purpura (ITP) and Hashimoto's disease with positivity for anticentromere antibody. The patient was a 64-year-old woman with symptoms of jaundice and general fatigue. About 30 year...

journal_title：Journal of gastroenterology

authors： Arakawa Y,Amaki S,Miyakawa H,Sakai T,Gotou I,Tanaka N,Moriyama M,Iwasaki A,Sugitani M,Arakawa Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Using cDNA microarray analysis that displays a total of 8734 mouse genes, we have identified 21 known and novel transcripts, including mouse expressed sequence tags (ESTs) that were consistently up- or downregulated in the fundus of wild-type mice and W/W(V) mice, where intramuscular interstitial cells of Ca...

journal_title：Journal of gastroenterology

authors： Daigo Y,Takayama I,Ward SM,Sanders KM,Fujino MA

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Alcohol-related diseases have multiple and varied associations with acetaldehyde, a highly toxic product of ethanol oxidation that accumulates in the absence of active aldehyde dehydrogenase (ALDH). This study was designed to clarify the role of acetaldehyde in liver injury, specifically in vivo and in vitro...

journal_title：Journal of gastroenterology

authors： Nakamura Y,Yokoyama H,Higuchi S,Hara S,Kato S,Ishii H

更新日期：2004-01-01 00:00:00

abstract：:A case of Dieulafoy's vascular malformation of the jejunum treated by laparoscopic surgery is described. The patient was a 31-year-old-woman who had complained of melena and had severe anemia needing blood transfusion. Angiography revealed microaneurysms and hypervascularity of the jejunum in the area between the firs...

journal_title：Journal of gastroenterology

authors： Mino A,Ogawa Y,Ishikawa T,Uchima Y,Yamazaki M,Nakamura S,Yukawa T,Matsumoto T,Arakawa T,Hirakawa K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The ideal medication for the treatment of acid-related diseases, for example, hemorrhagic ulcers and stress-related gastric bleeding, should have a rapid onset of action to promote hemostasis and alleviate symptoms. The aim of our study was to investigate the inhibitory effects on gastric acid secretion afte...

journal_title：Journal of gastroenterology

authors： Abe Y,Inamori M,Togawa J,Kikuchi T,Muramatsu K,Chiguchi G,Kawamura H,Kobayashi N,Kirikoshi H,Sakaguchi T,Takamura T,Nakajima A,Ueno N,Sekihara H

更新日期：2004-01-01 00:00:00

abstract：:We report a case of pancreas head carcinoma associated with fat replacement of the body and tail. A 68-year-old man presented with obstructive jaundice and was admitted to our hospital. Ultrasonography and computed tomography showed pancreas head tumor with a neighboring cystic lesion and fatty replacement of parenchy...

journal_title：Journal of gastroenterology

authors： Toyama N,Kamiyama H,Suminaga Y,Namai K,Ota M,Konishi F

更新日期：2004-01-01 00:00:00

abstract：:In vivo progression to malignancy is characterized by the switch to an angiogenic phenotype. The angiogenic switch is a critical control point for tumor expansion. The ability of a tumor to become neovascularized permits rapid expansion of tumor growth and increases the likelihood of metastases. The genetic alteration...

journal_title：Journal of gastroenterology

authors： Tanaka S,Sugimachi K,Yamashita Y,Shirabe K,Shimada M,Wands JR,Sugimachi K

更新日期：2003-03-01 00:00:00

abstract：:A patient with hepatitis C virus (HCV)-related liver cirrhosis and hepatocellular carcinoma (HCC) was treated successfully with an orthotopic liver transplantation (OLT) followed by interferon therapy. The 36-year-old Japanese man was diagnosed as having liver cirrhosis in 1983. HCC was detected in 1991, and by 1994, ...

journal_title：Journal of gastroenterology

authors： Shibata M,Yanaga K,Morizane T,Yanagawa T,Hirakawa M,Ueno Y,Esquivel CO,Mitamura K

更新日期：2003-01-01 00:00:00

abstract：:Chronic pancreatitis is a chronic clinical disorder characterized by irreversible damage to the pancreas and the development of histologic evidence of inflammation and fibrosis, and eventually the destruction and permanent loss of exocrine and endocrine tissue. A nationwide survey in Japan revealed an increase in the ...

journal_title：Journal of gastroenterology

authors： Otsuki M

更新日期：2003-01-01 00:00:00

abstract：:A case of granular cell tumor occurring in the sigmoid colon is reported. The patient, a 56-year-old man, visited our hospital for further evaluation of occult blood in his stool. Endoscopic examination revealed a yellowish, hemispheric submucosal tumor (SMT) with redness, about 6 mm in diameter, in the sigmoid colon....

journal_title：Journal of gastroenterology

authors： Endo S,Hirasaki S,Doi T,Endo H,Nishina T,Moriwaki T,Nakauchi M,Masumoto T,Tanimizu M,Hyodo I

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Subepithelial myofibroblasts (SEMFs) play a role in extracellular matrix (ECM) metabolism in the colon. In this study, we investigated the effects of interleukin (IL)-17, IL-1beta, and tumor necrosis factor (TNF)-alpha on matrix metalloproteinase (MMP)-3 secretion in colonic SEMFs. METHODS:MMP-3 secretion a...

journal_title：Journal of gastroenterology

authors： Bamba S,Andoh A,Yasui H,Araki Y,Bamba T,Fujiyama Y

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:In patients with hepatitis C virus (HCV)-genotype 1b and a high virus load, of more than 1 Meq/ml by the DNA probe assay, the clearance of HCV-RNA was achieved in only 10% with a 6-month interferon (IFN) course. We therefore assessed the efficacy of prolonged IFN therapy in patients with HCV-genotype 1b and ...

journal_title：Journal of gastroenterology

authors： Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Kobayashi M,Suzuki F,Akuta N,Someya T,Kumada H

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Although it is less frequently encountered, mesenteric vein occlusion poses as important a problem as mesenteric artery occlusion. The energy metabolism of intestinal tissue during venous occlusion and reperfusion was studied. METHODS:Male Wistar rats were studied in four groups of 17 animals each. Intestin...

journal_title：Journal of gastroenterology

authors： Kimura M,Kataoka M,Kuwabara Y,Sato A,Sugiura M,Fujii Y

更新日期：2003-01-01 00:00:00

abstract：:An association between macrovascular thrombosis and idiopathic inflammatory bowel disease has been described, although very few well-documented cases have been published. We report on a 39-year-old woman who presented with right hemifacial and upper limb edema that was shown to be due to an extensive right brachioceph...

journal_title：Journal of gastroenterology

authors： Ribeiro JM,Rebocho L,Lucas MB,Campos P,Victorino RM

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The clinicopathologic features of cystic neoplasms of the liver, such as cystadenoma and cystadenocarcinoma, are poorly defined because these lesions are extremely rare. METHODS:Clinicopathologic findings in six patients who underwent surgery for a cystic hepatic neoplasm were reviewed retrospectively to de...

journal_title：Journal of gastroenterology

authors： Hai S,Hirohashi K,Uenishi T,Yamamoto T,Shuto T,Tanaka H,Kubo S,Tanaka S,Kinoshita H

更新日期：2003-01-01 00:00:00